This daily doodle highlights some of the physical signs seen in hypercholesterolemia conditions, such as Familial Hypercholesterolemia. When cholesterol levels are high, they can deposit in various places in the body, including around the eyes which is termed xanthelasma palpebrarum. To note, deposits or lumps around the eye are not always caused by high levels of cholesterol and are not always seen in patients with high levels of cholesterol. Another physical sign of hypercholestorolemia that is shown in this daily doodle, is the gray ring around the outer margin of the iris, called arcus senilis.

Xanthomas on the Achilles tendon are specific to Familial Hypercholesterolemia.